# High blood pressure and ED: the condition, the medicines and the overlap > High blood pressure is on the NIH list of conditions that can lead to ED, because over time it can damage the blood vessels erections depend on. Some blood pressure medicines are linked to ED too. Do not stop one on your own: a prescriber can review the options, and ED medicines can be used alongside them with care. _Last updated: 2026-10-17_ --- **In short:** high blood pressure and erectile dysfunction (ED) overlap in two ways. The condition itself is on the National Institutes of Health (NIH) list of diseases that can lead to ED, because blood pressure that stays high for too long can damage blood vessels and reduce blood flow. Some of the medicines used to treat it are also linked to ED. That makes it hard to tell which one is behind a change, and the NIH says not to stop any medicine on your own. This guide covers the link, the medicines, what lowering blood pressure did in a large trial, what the ED medicine labels say about taking them with blood pressure treatment, and when to bring it up with a clinician. ## Can high blood pressure cause erectile dysfunction? Yes, high blood pressure can lead to ED. The NIH's National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) names it among the heart and blood vessel diseases most commonly behind ED, alongside atherosclerosis and stroke ([NIDDK, Symptoms & Causes of ED](https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction/symptoms-causes)), and its treatment page describes diabetes and high blood pressure as conditions "which can cause ED" ([NIDDK, Treatment for ED](https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction/treatment)). That is a statement about risk across many men, not a diagnosis for any one man. Age, other conditions, medicines, mood and habits can all play a part, which our guide to [what ED can signal about your health](/ed-and-your-health) covers. ## How does high blood pressure affect erections? It works mainly through the blood vessels. The American Heart Association (AHA) explains that blood pressure that remains high for too long can damage blood vessels and reduce blood flow throughout the body, and that ED can happen when not enough blood flows to the penis to allow an erection ([AHA, How High Blood Pressure Can Affect Your Sex Life](https://www.heart.org/en/health-topics/high-blood-pressure/health-threats-from-high-blood-pressure/how-high-blood-pressure-can-affect-your-sex-life)). A 2014 cardiology review describes the detail: high blood pressure can thicken the muscle in artery walls, narrow arteries through atherosclerosis and impair blood flow, and it can disturb the lining of the vessels (endothelial dysfunction) and the nitric oxide signal that lets them widen ([Viigimaa et al., World J Cardiol 2014](https://pmc.ncbi.nlm.nih.gov/articles/PMC4176800/)). Nitric oxide is also the signal sildenafil works through: the Viagra label describes nitric oxide release as part of the normal erection process and sildenafil as enhancing its effect (section 12.1) ([VIAGRA prescribing information, DailyMed](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0b0be196-0c62-461c-94f4-9a35339b4501)). Our page on [heart disease and ED](/ed-and-heart-disease) covers the wider circulation. ## How common is ED in men with high blood pressure? ED is common in men with high blood pressure, roughly twice as common as in men without it according to the 2014 review, which puts the relative risk at about two times that of men with normal blood pressure ([Viigimaa et al., World J Cardiol 2014](https://pmc.ncbi.nlm.nih.gov/articles/PMC4176800/)). The Systolic Blood Pressure Intervention Trial (SPRINT), a large US trial in adults aged 50 and over with high blood pressure, gives a sense of scale. Among 1,255 men in its erectile function study, 59.9% of those who were sexually active scored in the ED range on a standard 5-question survey ([Foy et al., J Sex Med 2019](https://pubmed.ncbi.nlm.nih.gov/30655182/)), and the follow-up report put self-reported ED at about two-thirds (66.1%) of the sample at the start ([Foy et al., J Sex Med 2020](https://pubmed.ncbi.nlm.nih.gov/31862174/)). These men were older and at raised heart risk, so the figures are not a prediction for any one man. | Source | Who was studied | What it found | | --------------------------- | --------------------------------------------------- | ----------------------------------------------------------------------------------- | | Viigimaa et al. 2014 review | Studies of men with essential hypertension | ED about twice as likely as in men with normal blood pressure | | SPRINT baseline (Foy 2019) | 1,255 men aged 50 or older with high blood pressure | 59.9% of sexually active men scored in the ED range | | SPRINT baseline (Foy 2019) | Same men, sexually active group | Lower systolic pressure and lower pulse pressure went with better erectile function | | SPRINT follow-up (Foy 2020) | Same 1,255 men | About two-thirds (66.1%) reported ED at the start | ## Is it the condition or the medicine? It can be either, and often both are in the picture, which is why it is worth working out with a prescriber rather than guessing. NIDDK lists high blood pressure as a condition that can lead to ED, and separately lists "blood pressure medicines and diuretics, or water pills" among the medicines that can have ED as a side effect ([NIDDK, Symptoms & Causes of ED](https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction/symptoms-causes)). MedlinePlus adds that a medicine that causes erection problems in one man may not affect another ([MedlinePlus, Drugs that may cause erection problems](https://medlineplus.gov/ency/article/004024.htm)). It can help to note for the appointment when the change started, for example before the diagnosis or after a new medicine or a dose change. Our guide to [medications that can affect erections](/medications-that-affect-erections) covers how a medication review works. ## Which blood pressure medicines are linked to ED? Thiazide diuretics and beta blockers come up most often. MedlinePlus says "thiazides are the most common cause of erectile dysfunction among the high blood pressure medicines," that beta blockers are next, and that alpha blockers tend to be less likely to cause it. Its list includes hydrochlorothiazide, chlorthalidone, atenolol, metoprolol, propranolol, clonidine, methyldopa, spironolactone and others ([MedlinePlus, Drugs that may cause erection problems](https://medlineplus.gov/ency/article/004024.htm)). The 2014 review reaches a similar picture and adds detail on other classes, as the table shows. It also notes "existing controversies" and says a definite causal link between blood pressure medicines and sexual problems has never been proven, so treat this as a general pattern rather than a rule for any one person ([Viigimaa et al., World J Cardiol 2014](https://pmc.ncbi.nlm.nih.gov/articles/PMC4176800/)). | Medicine class | What the sources say about erections | Source | | ---------------------------------------------- | --------------------------------------------------------------------------------------------------------------------------------------------------------- | ------------------- | | Thiazide diuretics (water pills) | Most common cause of ED among blood pressure medicines (MedlinePlus); the review says diuretics in general are negatively associated with sexual function | MedlinePlus; review | | Beta blockers, older types such as propranolol | Next most common; older beta blockers seen as the main culprits | MedlinePlus; review | | Beta blockers, newer types | Carvedilol and celiprolol less pronounced; nebivolol reported to improve ED in studies | Review | | Calcium channel blockers and ACE inhibitors | Seem to have a neutral effect (review), though MedlinePlus still lists some, such as nifedipine and enalapril | Review; MedlinePlus | | Angiotensin receptor blockers (ARBs) | Seem to affect erectile function positively | Review | | Alpha blockers | Tend to be less likely to cause ED | MedlinePlus | None of this means a particular medicine is wrong for you. Blood pressure medicines are chosen for many reasons beyond erections, and switching is a decision for the prescriber who knows the rest of your health. ## Should you stop a blood pressure medicine because of ED? No, not on your own. NIDDK says a health care professional may review your medicines, suggest a different dose or a different medicine, and adds: "Do not stop taking any medicines on your own. Talk with your health care professional first" ([NIDDK, Treatment for ED](https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction/treatment)). MedlinePlus goes further, warning that some medicines "may lead to life-threatening reactions if you do not take care when stopping or changing them" ([MedlinePlus, Drugs that may cause erection problems](https://medlineplus.gov/ency/article/004024.htm)). Stopping also leaves the high blood pressure itself untreated, and the condition is on the ED list in its own right, so the honest route is to tell your prescriber what has changed and let them weigh the options. ## Does lowering blood pressure improve erections? A large randomized trial found only a very small effect. In SPRINT, men with high blood pressure and raised heart risk (but without diabetes) were randomly assigned to a more intensive or a standard blood pressure target and followed for a median of about 3 years. The results differed by race and ethnicity, with slightly better scores in one group and slightly worse in another, and those differences were no longer statistically significant after adjusting for where men started. Among 280 men without ED at the start, the rate of new ED did not differ between the two groups. The authors concluded the effect of intensive treatment on erectile function "was very small overall and likely not of great clinical magnitude" ([Foy et al., J Sex Med 2020](https://pubmed.ncbi.nlm.nih.gov/31862174/)). That result is about erections only, and it is not a reason to change blood pressure treatment on your own. NIDDK points to quitting smoking, staying active, a healthy weight and limiting alcohol as habits that may help prevent or improve ED ([NIDDK, Treatment for ED](https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction/treatment)). ## Can ED pills be taken with blood pressure medicines? They can be, with care, and with one firm exception. The 2014 review says PDE5 inhibitors (the class that includes sildenafil and tadalafil) "can be safely and effectively administered" to people with high blood pressure, even when they take several blood pressure medicines, and that nitrates are the exception ([Viigimaa et al., World J Cardiol 2014](https://pmc.ncbi.nlm.nih.gov/articles/PMC4176800/)). The labels add the details. The Viagra label says sildenafil "may further lower blood pressure in patients taking anti-hypertensive medications," and that with alpha blockers the combination can in some patients "lower blood pressure significantly," leading to dizziness, lightheadedness or fainting (section 5.5). It also lists men taking blood pressure medicines and diuretics, and men with high blood pressure, among the groups in which Viagra was effective in trials ([VIAGRA prescribing information, DailyMed](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0b0be196-0c62-461c-94f4-9a35339b4501)). The Cialis label asks doctors to discuss with patients the potential for tadalafil to add to the blood-pressure-lowering effect of alpha blockers and blood pressure medicines (section 5.6) ([CIALIS prescribing information, DailyMed](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bcd8f8ab-81a2-4891-83db-24a0b0e25895)). | Combination studied in the label | Extra drop in blood pressure (systolic/diastolic, mm Hg), on average | Label | | -------------------------------------------- | ----------------------------------------------------------------------------- | -------------------------- | | Sildenafil with amlodipine | 8/7, lying down, in men with high blood pressure | Viagra, sections 7.3, 12.2 | | Tadalafil with amlodipine | 3/2 lying down in one study; no clinically significant difference in a second | Cialis, section 12.2 | | Tadalafil with an ARB (alone or with others) | 8/4 on ambulatory readings | Cialis, section 12.2 | | Tadalafil with bendrofluazide (a thiazide) | 6/4, lying down | Cialis, section 12.2 | | Tadalafil with enalapril (an ACE inhibitor) | 4/1, lying down | Cialis, section 12.2 | | Tadalafil with metoprolol (a beta blocker) | 5/3, lying down | Cialis, section 12.2 | The Cialis label calls these "small reductions" compared with placebo. The studies used set amounts of each medicine, which this page leaves out, because the choice of medicine and amount belongs to your prescriber. Alpha blockers carry extra label precautions, and nitrates for chest pain must never be combined with these medicines; our pages on [sildenafil interactions](/sildenafil-drug-interactions), [tadalafil interactions](/tadalafil-drug-interactions) and [nitrates and ED medications](/nitrates-and-ed-medications) cover those in full. ## Can low blood pressure cause erectile dysfunction? The sources we checked do not establish that. NIDDK's list of conditions that can lead to ED names high blood pressure, not low blood pressure ([NIDDK, Symptoms & Causes of ED](https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction/symptoms-causes)). Where low blood pressure clearly matters is with ED medicines. The Viagra label says sildenafil caused temporary drops in lying-down blood pressure in healthy volunteers (an average maximum fall of 8.4/5.5 mm Hg), and that there are no controlled clinical data on its safety or effectiveness in men with resting low blood pressure below 90/50, or with high blood pressure above 170/110; if it is prescribed for them, the label says to do so with caution ([VIAGRA prescribing information, section 5.1, DailyMed](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0b0be196-0c62-461c-94f4-9a35339b4501)). If you have low blood pressure, or get dizzy on standing, say so before any ED medicine is prescribed. ## Can ED be an early warning sign? It can be a reason to get your blood pressure and heart checked. The AHA says ED "can be a sign for a healthcare professional to check for high blood pressure and other problems" ([AHA, How High Blood Pressure Can Affect Your Sex Life](https://www.heart.org/en/health-topics/high-blood-pressure/health-threats-from-high-blood-pressure/how-high-blood-pressure-can-affect-your-sex-life)). The 2014 review explains a theory behind this: the smaller arteries of the penis may show damage before larger ones such as the heart's arteries, and in the studies it cites ED appeared more than three years before coronary artery disease became apparent ([Viigimaa et al., World J Cardiol 2014](https://pmc.ncbi.nlm.nih.gov/articles/PMC4176800/)). ED on its own does not mean you have high blood pressure or heart disease. It is a sensible prompt for a checkup, which our guide to [heart disease and ED](/ed-and-heart-disease) walks through. Bring up ED with whoever manages your blood pressure, especially if it started or changed after a new medicine or a dose change. Bring a list of everything you take, including over-the-counter products and anything for chest pain. Do not stop a blood pressure medicine on your own. If you take an ED medicine, NIDDK says to call your health care professional right away for an erection lasting longer than 4 hours or for vision or hearing loss. ## The bottom line High blood pressure is one of the conditions the NIH links to ED, mainly through damage to blood vessels, and some blood pressure medicines, thiazides and older beta blockers most often, are linked to it too. Telling the two apart is a job for your prescriber, and stopping a medicine on your own is the one step every source warns against. Tighter blood pressure control changed erectile function very little in a large trial. ED medicines can be used alongside blood pressure treatment with care, never with nitrates, and the right choice depends on your full health picture. ## Sources Every clinical statement on this page traces to a primary or guideline source: - [NIH NIDDK, Symptoms & Causes of Erectile Dysfunction (last reviewed October 2024)](https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction/symptoms-causes): high blood pressure among the heart and blood vessel diseases that can lead to ED; blood pressure medicines and diuretics among the medicines that can cause ED. - [NIH NIDDK, Treatment for Erectile Dysfunction (last reviewed October 2024)](https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction/treatment): medicine review, a different dose or medicine, and "Do not stop taking any medicines on your own"; high blood pressure as a condition that can cause ED; lifestyle steps; seeking care for an erection lasting longer than 4 hours. - [American Heart Association, How High Blood Pressure Can Affect Your Sex Life (last reviewed May 9, 2024)](https://www.heart.org/en/health-topics/high-blood-pressure/health-threats-from-high-blood-pressure/how-high-blood-pressure-can-affect-your-sex-life): blood vessel damage and reduced blood flow; ED as a sign to check for high blood pressure. - [MedlinePlus, Drugs that may cause erection problems (reviewed January 2025)](https://medlineplus.gov/ency/article/004024.htm): blood pressure medicines and diuretics linked to ED; thiazides most common, then beta blockers, alpha blockers less likely; never stop a medicine without talking to your provider. - [Viigimaa M, Vlachopoulos C, Lazaridis A, Doumas M. Management of erectile dysfunction in hypertension: Tips and tricks (World J Cardiol, 2014)](https://pmc.ncbi.nlm.nih.gov/articles/PMC4176800/): about twofold higher ED risk with hypertension; structural and functional artery changes; effects of blood pressure medicine classes and no proven causal link; PDE5 inhibitors with blood pressure medicines, nitrates and alpha blockers; artery size hypothesis and ED before coronary artery disease. - [Foy CG, et al. Blood Pressure, Sexual Activity, and Erectile Function in Hypertensive Men: Baseline Findings from SPRINT (J Sex Med, 2019)](https://pubmed.ncbi.nlm.nih.gov/30655182/): 1,255 men aged 50 or older; 59.9% of sexually active men in the ED range; blood pressure measures associated with erectile function. - [Foy CG, et al. Effect of Intensive vs Standard Blood Pressure Treatment Upon Erectile Function in Hypertensive Men: Findings From SPRINT (J Sex Med, 2020)](https://pubmed.ncbi.nlm.nih.gov/31862174/): 66.1% with ED at baseline; differences by race and ethnicity; no difference in new ED among 280 men; effect "very small overall." - [VIAGRA (sildenafil citrate) prescribing information, DailyMed](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0b0be196-0c62-461c-94f4-9a35339b4501): section 5.1 (temporary blood pressure drops; no controlled data below 90/50 or above 170/110), 5.5 (alpha blockers and blood pressure medicines), 7.3 and 12.2 (amlodipine study), 12.1 (nitric oxide and how sildenafil works), and 14 (effective in men with hypertension and men taking blood pressure medicines and diuretics). - [CIALIS (tadalafil) prescribing information, DailyMed](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bcd8f8ab-81a2-4891-83db-24a0b0e25895): section 5.6 (alpha blockers and blood pressure medicines), 7.1 and 12.2 (amlodipine, ARB, bendrofluazide, enalapril and metoprolol studies). --- _Affiliate disclosure: some links on the web version of this site go to Bodybuilding Peptides (trybbpeptides.com), an affiliate destination, and we may earn a commission if you buy there. Our coverage is independent of that relationship. Details: https://theedreport.com/affiliate-disclosure/_